by Floris-Jan Zuure
July 14, 2025

360-DEGREE APPROACH IN MALE FACIAL AESTHETICS: HOW TO ENHANCE YOUR LOOK WITH THE POWER OF SYNERGY

360-DEGREE APPROACH IN MALE FACIAL AESTHETICS: HOW TO ENHANCE YOUR LOOK WITH THE POWER OF SYNERGY

Written by Dr Pieter Siebenga – Cosmetic Doctor, in collaboration with and edited by Salon d’Homme.

WHY MEN ARE RETHINKING FACIAL AESTHETICS

The field of male facial aesthetics has evolved significantly. More men are seeking ways to improve their appearance, not out of insecurity, but from a growing awareness that taking care of your skin and facial harmony is part of modern self-care. As techniques and products become more advanced, the goal is no longer to look "done," but to age with intention, combining effectiveness with subtlety.

INJECTABLE OPTIONS DESIGNED FOR MEN

Injectable treatments are the foundation of many aesthetic strategies. However, anatomical and physiological differences in male faces require a distinct approach.

  • Botox (Botulinum Toxin A): This neuromodulator temporarily relaxes specific muscles to reduce dynamic wrinkles such as frown lines and crow's feet. Men often need higher doses due to stronger muscle mass, especially in the glabella (frown), forehead and around the eyes (1). Technique is crucial to avoid brow ptosis, a drooping of the eyebrow that can occur if the muscle is overly relaxed (1).
  • Hyaluronic Acid (HA) fillers: These are gel-like substances that restore volume and reshape contours (2). In men, they're used to subtly enhance the midface and sharpen the jawline, without feminising features (2). Understanding male facial anatomy is essential to achieve natural results.

BEYOND CORRECTION: BIOREGENERATIVE SOLUTIONS

Traditional injectables offer immediate structural change, but today’s regenerative medicine goes deeper, stimulating the skin’s own repair systems.

  • Poly-L-lactic acid (Julaine): Encourages collagen production gradually over months, restoring elasticity and volume with long-lasting effects (3).
  • PRP (Platelet-Rich Plasma): Uses concentrated growth factors from your own blood to support healing and regeneration (4). Especially effective when combined with microneedling.
  • Polynucleotides (Philart): Also known as "salmon DNA" or "salmon sperm," these molecules stimulate collagen, elastin and hydration (5). Excellent for improving skin texture and density, including in delicate areas like around the eyes (6).
  • Hyperdiluted Radiesse: A calcium-based injectable that enhances collagen production while improving skin quality and firmness. Results become visible as early as four weeks after treatment (7).
  • Profhilo & Profhilo Structura: Ultra-pure hyaluronic acid treatments that improve hydration, elasticity and fat tissue quality, subtly lifting and firming the face (8). Treatment typically consists of two sessions with a 30-day interval (9).

These treatments don’t just fill, they restore and regenerate. And are recommended by Dr. Pieter Siebenga based on an initial orientation consultation.

THE 360-DEGREE APPROACH: OUTSIDE IN MEETS INSIDE OUT

Synergy matters. Combining injectable treatments as outlined above with Salon d'Homme's skincare treatments and tailored product routines leads to more profound and longer lasting results (10, 11, 12). These complementary approaches work together by addressing different layers and functions of the skin: injectables improve structure and stimulate regeneration from within, while advanced facials and personalised skincare protect the skin barrier, enhance active ingredient delivery, and maintain overall skin health between sessions.

Combining injectable treatments with Salon d'Homme's skincare treatments and tailored product routines leads to more profound and longer lasting results.

SCIENTIFIC MECHANISMS BEHIND SYNERGY

  • Enhanced absorption: Microneedling creates micro-channels that allow active skincare ingredients to penetrate deeper (13).
  • Complementary cellular stimulation: Different treatments stimulate skin regeneration through unique mechanisms. HA-based injectables offer immediate hydration and volume, while biostimulatory options like hyperdiluted Radiesse or microneedling encourage long-term collagen production. Studies show these effects are enhanced when combined (14).
  • Greater longevity: Combinations of treatments can improve the duration of individual treatments. Research shows that when botulinum toxin (botox) is coupled with microneedling, the neuromodulator's effects remain longer due to increased absorption and collagen remodeling triggered by the microneedling procedure (15).
  • Full-spectrum targeting: Injectables reach the deeper layers; skin therapies address the surface and upper dermis. Together they create a more complete outcome (16).

SKINCARE TREATMENTS & PRODUCTS THAT SUPPORT AESTHETIC RESULTS

At Salon d’Homme, we work according to three core pillars: effective in-clinic treatments, tailored skincare routines at home, and ongoing education. To fully optimise the effects of aesthetic regenerative injectables, our skincare treatments play an essential role in both preparation and recovery.

  • Signature Face Treatment: Professional facials provide essential preparation and maintenance for injectable treatments. Deep cleansing prepares the skin by removing impurities and balancing skin pH (17). Specialised facial techniques improve circulation and lymphatic drainage, enhancing the skin's responsiveness to injectables (17). These targeted treatments also help accelerate recovery and minimise side effects (17).
  • Chemical Peel Treatment: Chemical peels work synergistically with injectable treatments by removing damaged outer layers of skin and stimulating surface renewal (18). This enhances tone, texture, and creates a more receptive environment for topical treatments such as Profhilo (18). Research also shows that combining botulinum toxin with chemical peels produces superior results for facial rejuvenation compared to either treatment alone (16).
  • Microneedling Treatment: Microneedling creates a potent synergy with injectable treatments. When combined with biostimulatory injectables like hyperdiluted Radiesse or polynucleotides, it can produce up to a 400% increase in collagen production compared to either treatment alone (14). The micro-channels created during treatment allow for deeper penetration of active ingredients, significantly improving their efficacy (13). Microneedling and dermal fillers stimulate collagen production through different pathways that, when combined, result in more comprehensive skin remodelling (13).

At Salon d’Homme, every skincare treatment begins with a lymphatic drainage massage. This gentle technique stimulates lymph flow, reduces puffiness, enhances circulation, and improves nutrient delivery to facial tissues, supporting overall results and recovery (19).

A consistent skincare routine at home maximises the effects of in-clinic treatments (8). This includes a simple but effective three step routine using targeted antioxidants, daily SPF, and hydration with barrier supporting ingredients. These products help maintain and extend results, support recovery, and protect against environmental stressors (8).

CONCLUSION: SKIN QUALITY OVER CORRECTION

We are witnessing a clear shift in aesthetics: away from overfilled results and toward subtle, science-based skin regeneration. At Salon d’Homme, we combine precision skin therapy with the regenerative expertise of Dr Pieter Siebenga to deliver natural results from the outside in and inside out.

This is the new standard: results that age with you, not against you.

REFERENCES

  1. Carruthers J, Carruthers A. Botulinum toxin in men: review of relevant anatomy and clinical trial data. Dermatol Surg. 2013 Oct;39(10):1434-43.
  2. Braz A, et al. Midface Rejuvenation Using Juvederm Fillers in Male Patients. J Cutan Aesthet Surg. 2022 Jan-Mar;15(1):20-28.
  3. Bohnert K, et al. Randomized, controlled, multicentered, double-blind investigation of injectable poly-L-lactic acid for improving skin quality. Dermatol Surg. 2019 May;45(5):718-724.
  4. Maisel-Campbell AL, et al. A systematic review of the safety and effectiveness of platelet-rich plasma (PRP) for skin aging. Arch Dermatol Res. 2020 Jul;312(5):301-315.
  5. Pak CS, et al. The safety and efficacy of poly-L-lactic acid and polynucleotide mixture filler for nasolabial folds: A 24-week prospective, randomized, double-blinded, split-face study. J Cosmet Dermatol. 2021 Jun;20(6):1846-1853.
  6. Choi YJ, et al. Comparative Evaluation of the Effectiveness of Novel Hyaluronic Acid-Polynucleotide Complex Dermal Filler. Nature. 2020 Mar 20.
  7. Alam M, et al. Calcium hydroxylapatite for augmentation of face and hands: A retrospective analysis of radiographic assessment. Dermatol Surg. 2020 Dec;46(12):1602-1607.
  8. Sparavigna A, et al. Efficacy and tolerance of an injectable medical device containing stable hybrid cooperative complexes of high- and low-molecular-weight hyaluronic acid: a monocentric 16 weeks open-label evaluation. Clin Cosmet Investig Dermatol. 2016 Oct 26;9:297-305.
  9. Beatini A, et al. Hyaluronic acid filler technique with a focus on the anatomy of the face. Dermatol Surg. 2021 Jun 1;47(6):827-834.
  10. Reilly DM, et al. Regenerative and stem cell-based techniques for facial rejuvenation. Facial Plast Surg Aesthet Med. 2021 Jul-Aug;23(4):232-240.
  11. Beam Skin. The synergy of injectables and skin treatments. 2023 Sep 22.
  12. Aesthetic Medicine. THE SYNERGY OF DERMAL FILLERS AND DEVICES. 2025 Jan 01.
  13. Iriarte C, et al. Review of applications of microneedling in dermatology. Clin Cosmet Investig Dermatol. 2017 Aug 8;10:289-298.
  14. Alam M, et al. Combination treatment of microneedling and platelet-rich plasma for skin rejuvenation: A systematic review and meta-analysis. Dermatol Surg. 2021 Apr 1;47(4):573-581.
  15. Rare IL. Combining Microneedling with Botox: Synergistic Effects for Facial Rejuvenation. 2024 Feb 07.
  16. Hölzle F, et al. Biological Effects of Hyaluronic Acid-Based Dermal Fillers and Laser Treatment. J Drugs Dermatol. 2020 Sep 01;19(9):897-899.
  17. Abdelgawad AA, et al. Microneedling combined with botulinum toxin-A versus microneedling combined with platelet-rich plasma in treatment of atrophic acne scars. PubMed. 2022 Nov 05.
  18. Synergy Toledo. Injectables - Synergy Primary Care & Wellness. 2023 Jun 16.
  19. Gupta AK, et al. A systematic review of platelet-rich plasma's efficacy for androgenetic alopecia. J Dermatolog Treat. 2019 Aug;30(5):417-425.